Vaccine-Acquired Rotavirus in Infants with Severe Combined Immunodeficiency
نویسندگان
چکیده
منابع مشابه
Vaccine-acquired rotavirus in infants with severe combined immunodeficiency.
Live pentavalent human-bovine reassortant rotavirus vaccine is recommended in the United States for routine immunization of infants. We describe three infants, two with failure to thrive, who had dehydration and diarrhea within 1 month after their first or second rotavirus immunization and subsequently received a diagnosis of severe combined immunodeficiency. Rotavirus was detected, by means of...
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Rotaviruses are important pathogens of human infants and the infants of many animal species. The disease produced by these viruses can be described as an acute, self-limiting diarrheal disease, with virus replication localized to the differentiated epithelial enterocytes of the small intestine. Immunologically normal infants shed virus for approximately 5 to 12 days after the onset of infection...
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Newborn screening for severe combined immunodeficiency (SCID) is currently being performed in many states. It is important to address diagnostic challenges while outcomes are emerging from the first several years of screening. We present the case of a premature infant whose initial newborn screen was strongly positive for SCID. Subsequent lymphocyte subset analysis by flow cytometry was difficu...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2010
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa0904485